Oct-2021 Holistic Management of Advanced PCa – See Beyond the Prostate
Speakers: Professor Neal Shore (Carolina Urologic Research Centre, USA), Dr. Warren Lo (Hospital Kuala Lumpur, Malaysia), Dr. NG Choon Ta (National Heart Centre, Singapore)
Moderated by Prof. Ong Teng Aik from Malaysia, this webinar invited 3 faculty speakers to share how to optimize androgen deprivation therapy for advanced prostate cancer patients. In particular, patients in the PRONOUNCE study were intensively monitored with treatments optimized in tertiary centres with multidisciplinary care, a situation not always reflective of real-world settings. Several real-world analyses and RCT (HERO) have consistently highlighted higher incidence rates of MACE with GnRH agonists. There is a tighter T and FSH suppression with GnRH antagonist compared to agonist. Upfront combination therapy + ADT for mHSPC should be considered early to improve prognosis, esp. for patients with high risk features.
